Dry syrups are the mixtures that require the addition of water at the time of dispensing inadequate chemical stability of drug in aqueous vehicle to avoid the physical stability problem.
Cefixime is in a group of drugs called cephalosporin antibiotics. Cefixime is used to treat many different types of infections caused by bacteria. Your symptoms may get better before the infection is completely treated. Cefixime will not treat a viral infection such as the common cold or flu.
It has been demonstrated by recent studies that Cefixime shows significantly better symptoms relief with the modest improvement of bacterial infection.
Indications and Usage
● Urinary tract infections caused by Escherichia coli and Proteus mirabilis.
● Otitis media caused by Haemophilus influenza.
● Onsillitis caused by S. pyogenes.
● Uncomplicated gonorrhea caused by Neisseria gonorrhoeae.
Mechanism of Action
Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.
Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications. Probenecid may increase the serum level of cefixime.
● Caution when used during pregnancy.
● Caution when used during lactation.
● Hypersensitivity to cephalosporin.
● Mild nausea
● Stomach pain