Before knowing its combination, we should need to know that how they work individually, so you know that Etoricoxib is Anti-inflammatory medicines (NSAIDs), used to relieve pain, swelling, and other symptoms of inflammation and Thiocolchicoside (TCC) is used clinically for its muscle relaxant, anti-inflammatory, and analgesic properties.
Indications and Usage
- Rheumatoid arthritis: Rheumatoid arthritis is a disorder in which joint cartilage becomes inflamed and, over time destroyed.
- Gout: Gout is a condition in which uric acid crystals accumulate within the cartilage of joints, resulting in extreme pain and inflammation.
- Osteoarthritis: Osteoarthritis concerns the gradual and irreversible degradation of the cartilage located within bone joints.
- Ankylosing spondylitis: In this disorder, the joints between the vertebrae in the spinal column come under attack by the immune system, and cause inflammation.
Etoricoxib selectively inhibits cyclooxygenase 2 (COX-2).
|Metabolism||Hepatic, CYP extensively involved (mainly CYP3A4)|
|Excretion||Renal (70%) and fecal (20%)|
Mode of Action
It has been demonstrated by recent studies concomitant administration of an Etoricoxib and Thiocolchicoside shows significantly better symptoms relief compared with the modest improvement of inflammation with each of the treatment alone.
If you suffer from serious side effects, then concern your doctor as soon as possible.