VIEW VIDEO

Watch Video

Recent Launched Product
Umeco-Vit Capsule Mecobalamin, Alpha Lipoic Acid, Vitamin B1, Vitamin B6 & Folic Acid
Yonizex-SG Capsule Natural Extract, Vitamins & Minerals
Smaclif Plus Tablets Aceclofenac & Paracetamol
Ucozeth-500mg Tablet Azithromycin 500 mg
Yonikast-L Tablet Levocetirizine 5 mg, Montelukast 10 mg
Yonizex-L Syrup Lycopene with Multivitamins & Multiminerals

YONIKAST-FX

₹119

Fexofendine 120 mg, Montelukast 10 mg Tablets


Montelukast is a Leukotriene receptor antagonists. (is used for maintenance treatment of asthma and to relive symptoms of seasonal allergies) It is a selective and orally active leukotrien antagonist that inhibits the cysteinyl leukotrien CysLT1 receptor.

Fexofenadine Hydrochloride is a second - generation antihistamine pharmaceutical drug (is prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of hay fever).

Indications & Usage

Asthma, Chronic Allergic, Seasonal Allergies, Used For Hay Fever or Allergies.

Rationale of Combination

This drug continues to work for 12 hr - 24 hr. A large study found that Cetirizine was associated with an increased risk of heat arrhythmias comparison to Fexofenadine.
It has been demonstrated by recent studies that the treatment of allergic rhinitis with concomitant administration of an antileukotrien (montelukast) and an antihistamine (Fexofenadine), shows significantly better symptoms relief compared with the modest improvement of rhinitis symptomatology with each of the treatments alone.

  (FEXOFENADINE HCL) (MONTELUKAST)
  HAY FEVER OR ALLERGIES ASTHMA
What is it? A bodily reaction to usually harm - less substances in the environment - most often pollen, mold, and animal dander. A condition in which the tubes in the lungs become swollen and narrow, making it difficult to breathe and get enough oxygen in and out of your lungs. Can be triggered by pollen, mold, dander, smoke and air pollution, exercise, other illness, stress, and some drugs.
Why do some people get it? Generic predisposition Generic predisposition
  Can strike people of all ages, but often shows up in childhood and teen years. Infection can trigger asthma
    Usually shows up in childhood; less commonly strikes over age 25.
Main Symptoms Sneezing Mild attacks:
  Teary eyes Feeling out of breath
  Itchy nose and throat Tightness in chest
  Congestion, runny nose Wheezing
  Clear nasal discharge Coughing
  Cough(Sometimes)  
    Severe attacks:
  Difficulty breathing (sometimes) Very difficult to breath
  Headache (sometimes) Difficulty talking
    Skin feels if it's pulled tightly around ribs and neck
  Itchy red patches on skin (hives) Rapid heartbeat
Main Treatment Options Nasal Sprays Inhalers and nebulizers containing short acting bronchodilators.
  Antihistamine Inhalers containing steroids
  Decongestants Leukotriene - block pills
  Allergy shots Steroid pills or shots
    Immune - system modifiers


Drug Interactions

BEFORE TAKING THIS MEDICINE TELL THE DOCTOR ABOUT ANY MEDICAL PROBLEMS AN ALLERGIES RELATED ASTHMA. Some medicines may affect how patient's works, or other medicine work. If anyone is taking or has recently taken other medicines, including those obtained without a prescription.
Theophylline, predisolone, oral contraceptives, terfenadine, digoxin, warafin, thyroid hormones & sedative hypnotics, Antifungal medicine (ketokonazole), aspirin, fruit juice.theophylline, erythromycin, antacids, cimetidine

Indications

● Montelukast causes inhibition of airway cysteinyl leukotriene receptors as demonstrated by the ability to inhibit bronchoconstriction due to inhaled LTD 4 in asthmatics.
● For Chronic Allergic conditions like seasonal allergic rhinitis, perennial allergic rhinitis, Rhinitis associated with Ashtma.
● Monteluakst may offer an alternative to Theophylline as add - on therapy is asthma poorly controlled by short acting beta - agonist and inhaled corticosteroids.
● Montelukast causes inhibition of airway cysteinyl leukotriene receptors as demonstrated by the ability to inhibit bronchoconstriction due to inhaled LTD 4 in asthmatics.
● For Chronic Allergic conditions like seasonal allergic rhinitis, perennial allergic rhinitis, Rhinitis associated with Ashtma.
Monteluakst may offer an alternative to Theophylline as add - on therapy is asthma poorly controlled by short acting beta - agonist and inhaled corticosteroids.

Fexofenadine is antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms sneezing, itching, watery eyes, and runny nose.
It is used to treat the symptoms a seasonal allergies (hay fever) in adults and children also used in skin itching and hives caused by a conditions called chronic idiopathic urticaria in adults and children.

Adverse Effects

● Nausea, diarrhea, upset stomach
● Menstrual cramps
● Drowsiness, Tired feeling.
● The most commonly reported adverse reactions were headache, asthma and upper respiratory tract infections; however none were significantly different in frequency between the groups.

Contraindications

Hypersensitivity, pregnant patients, patients with blood and lymphatic system disorder and psychiatric disorder.

Conclusion

This is a new combination for severe allergy which could be a sign of asthma; most people who have asthma also have underlying allergies can take this medicine. In people who have allergies and allergy - induced asthma the body's immune system overreacts when exposed to otherwise harmless substances, such as pollen, dust mites, mold spores, and animal dander. In people with allergies are at much higher risk of developing asthma and sinus infections (sinusitis) and the inflammation that a compares the allergic response can damage the respiratory system and make more susceptible to lung infection like pneumonia.
Asthma often co-exists in patients with persistent allergic rhinitis. The combination of Fexofenadine + Montelukast equally reduces the serum SICAM - 1 concentration and gives the same clinical effect in pateings The study shows to investigate the effects of treatment with a combination of antihistamine (Fexofenadine) and an antileukortiene (Montelukast) in patients with persistent allergic rhinitis and newly diagnosed asthma.
The use of Moneluakst in the treatment of seasonal allertic rhinitis is more effective than placebo, an effective as Loratidine and in combination with antihistamine is perhaps more effective for allevialing congestion symptoms than antihistamine alone. From the above discussion, it can be concluded that this medicine could improve the quality of life of patients with allergic rhinitis as well as asthma in addition to being efficacious as immunotherapy in seasonal allergic rhinitis. Moreover it has a considerable safety profile, with persistent results. This combination offers as effective, well tolerated and convent treatment option for children with asthma and allergies.

Contact Details

For More Information, Check below!